Abstract Insulin resistance, a hallmark of metabolic disorders such as type 2 diabetes mellitus (T2DM) and obesity, is characterized by a diminished cellular response to insulin, leading to impaired glucose uptake and utilization. Intermittent fasting […]
Summary Researchers have developed a groundbreaking vascularized model of stem cell-derived islet cells, offering new hope for diabetes treatment. This model mimics the natural environment of the pancreas more effectively than previous models, paving the […]
Beyond Islets: A Comprehensive Review of Vascularization Strategies in Tissue Engineering and Regenerative Medicine Abstract Vascularization, the formation of functional blood vessel networks, is a critical bottleneck in the advancement of tissue engineering and regenerative […]
Summary Scientists have identified the PPP1R3B gene as a key regulator of how the liver stores energy, impacting metabolic disease risk. This discovery paves the way for personalized treatments for type 2 diabetes and fatty […]
Abstract Triglycerides (TGs) represent the primary long-term energy storage molecule in eukaryotes, crucial for maintaining energy homeostasis. Their metabolism, encompassing synthesis, storage, and breakdown, is a complex, tightly regulated process with profound implications for overall […]
Abstract Glycogen, a branched polymer of glucose, serves as the primary short-term energy reserve in animals and fungi. This research report provides an in-depth review of glycogen metabolism, encompassing the intricate regulatory mechanisms governing its […]
Summary This article provides ten actionable steps for hospitals to enhance their data security. It covers crucial aspects like staff training, access control, encryption, and incident response planning. By following these best practices, hospitals can […]
Summary This article explores the latest advancements in treating childhood rhabdomyosarcoma (RMS), focusing on innovative therapies for primary and recurrent cases. We discuss the evolution of treatment strategies, including chemotherapy, targeted therapies, and immunotherapies, and […]
Rhabdomyosarcoma: A Comprehensive Review of Subtypes, Molecular Biology, Clinical Management, and Emerging Therapeutic Strategies Abstract Rhabdomyosarcoma (RMS) is an aggressive soft tissue sarcoma that predominantly affects children and adolescents. Despite advancements in multi-modal therapy, including […]
Summary A new AI test helps determine which prostate cancer patients will benefit from abiraterone, potentially improving outcomes and reducing unnecessary side effects. The test analyzes tumor samples, identifying those who are most likely to […]
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