Abstract Beta-cells, the sole producers of insulin within the pancreatic islets of Langerhans, are critical for glucose homeostasis. Their dysfunction or destruction leads to diabetes mellitus, with Type 1 Diabetes (T1D) characterized by autoimmune-mediated beta-cell […]
Abstract Denosumab, a monoclonal antibody targeting Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL), is a well-established therapeutic agent for osteoporosis and bone metastases. Its mechanism of action, primarily focused on inhibiting osteoclast activity, has […]
Summary This article explores the groundbreaking research on the use of statins in patients with chronic liver disease. Studies show a link between statin use and reduced risks of liver complications, including liver cancer and […]
Abstract Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, are among the most widely prescribed medications globally, primarily for their efficacy in reducing low-density lipoprotein cholesterol (LDL-C) and preventing cardiovascular disease (CVD). This comprehensive review delves […]
Summary This article discusses the significant digital health transformation happening in the Middle East and North Africa (MENA) region. It highlights the role of HIMSS25 Changemakers, the challenges faced, and the innovative solutions being implemented. […]
Summary Quibim’s QP-Prostate, an AI-powered radiology tool, has received FDA authorization, marking a significant advancement in prostate cancer detection. This innovative software uses MRI scans to identify cancerous lesions with increased accuracy and efficiency, potentially […]
Revolutionizing Prostate Cancer Detection and Management: A Comprehensive Overview of AI Integration, Current Landscape, and Future Directions Many thanks to our sponsor Esdebe who helped us prepare this research report. Abstract Prostate cancer (PCa) remains […]
Summary This article discusses the alarming resurgence of measles and emphasizes the importance of protecting immunocompromised children. It explores the challenges in determining immunity in this group, highlights new research advocating for age-appropriate antibody thresholds, […]
Abstract Antibody thresholds, widely used to assess immunity to various infectious diseases, are primarily derived from adult populations and often applied indiscriminately across all age groups. This practice presents significant limitations, particularly when evaluating immunity […]
Abstract Immunocompromised children represent a heterogeneous population facing significantly amplified risks from infectious diseases. This report provides a comprehensive overview of the diverse etiologies of pediatric immunodeficiency, ranging from congenital disorders to acquired conditions stemming […]
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